Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase
نویسندگان
چکیده
We purified CALLA from human kidney and isolated a cDNA clone reactive with two oligonucleotide probes corresponding to two distinct peptides. The amino acid sequence translated from the CALLA cDNA revealed 100% identity with that of human neutral endopeptidase (NEP, enkephalinase). The distribution of CALLA antigen and NEP in normal tissues are similar.
منابع مشابه
MME ( membrane metallo - endopeptidase )
Location: 3q25.2 Note: Membrane metallo-endopeptidase (MME) is a 100-kD type II transmembrane glycoprotein originally described on human acute lymphoblastic leukemia cell lines and therefore it was originally designated as common acute lymphocytic leukemia antigen (CALLA). MME is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several pept...
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عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 168 شماره
صفحات -
تاریخ انتشار 1988